Identification of the origin of epigenetic abnormalities in cancer cells by use of the cellular reprogramming technique
Associate professor, Graduate School of Medicine,
Epigenetic abnormality is one of the most common alterations in cancers. Recent evidences indicate that such epigenetic alterations play a pivotal role in the carcinogenesis. However, the origin of the alterations is by no means clear. The aim of this project is to identify the origin of epigenetic abnormalities in cancer cells using a cellular reprogramming technique, and to apply the findings for the development of a new therapeutic strategy to treat cancer patients.